Table 1.
Patient, disease and transplant characteristics by weight groups
| < 125% of IBW (n=46) | ≥ 125% of IBW (n=45) | |
|---|---|---|
| Male | 30 (65%) | 24 (53%) |
| Age, median (range) | 58 (22–74) | 59 (34–75) |
| BMI, median (range) | 24.5 (18–29) | 31.9 (26–49) |
| Weight (kg), median (range) | 70 (41–105) | 95 (66–139) |
| Lymphoma Diagnosis | ||
| Diffuse large B cell NHL | 21 (46%) | 30 (67%) |
| Mantle cell lymphoma | 11 (24%) | 8 (18%) |
| Follicular NHL | 5 (11%) | 4 (9%) |
| T cell NHL | 7 (15%) | 1 (2%) |
| Other* | 2 (4%) | 2 (4%) |
| Disease status | ||
| CR | 33 (72%) | 30 (67%) |
| PIF/REL sensitive | 12 (26%) | 14 (31%) |
| Stable disease | 1 (2%) | 1 (2%) |
| Months from dx to HCT, median (range) | 10 (3–113) | 19 (3–250) |
| Karnofsky score | ||
| 100 | 21 (46%) | 22 (49%) |
| 90 | 17 (37%) | 20 (44%) |
| 80 | 8 (17%) | 3 (7%) |
| HCT-CI | ||
| 0 | 18 (39%) | 18 (40%) |
| 1–2 | 17 (37%) | 19 (42%) |
| > 2 | 10 (22%) | 8 (18%) |
| Unknown | 1 (2%) | 0 (0%) |
| Year of HCT | ||
| 2013 | 6 (13%) | 4 (9%) |
| 2014 | 16 (35%) | 16 (36%) |
| 2015 | 24 (52%) | 25 (56%) |
| TNC infused × 108/kg, mean (SD) | 15.0 (8.4) | 14.8 (9.5) |
| CD34+ cells infused × 106/kg, mean (SD) | 5.2 (3.5) | 4.9 (2.2) |
IBW, ideal body weight; BMI, body mass index; HCT-CI, Hematopoietic Cell Transplantation-Comorbidity Index. TNC, total nucleated cell. N (% of column total) reported for categorical variables; median (range) or mean (SD) for continuous variables.
*
Other diagnoses consisted of HIV-associated primary effusion lymphoma and lymphomatoid granulomatosis in the non-obese group and Hodgkin’s and Burkitt’s lymphoma in the obese group.