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. 2017 Feb 28;9(6):300–309. doi: 10.4254/wjh.v9.i6.300

Figure 4.

Figure 4

Combined hepatocellular-cholangiocarcinoma with stem cell features, cholangiocellular subtype. A: H and E, 4 × - tumor cells present in tubular, anastomosing (antler-like) pattern; B: H and E, 10 × - small hyperchromatic tumor cells with high nuclear to cytoplasmic ratio present within dense fibrous stroma; C: CK7, 10 × - tumor is diffusely positive for CK7; D: CD56, 10 × - CD56 staining the cholangiolocellular component as well as the tumor cells at the periphery of the trabeculae. The tumor was diffusely positive for CK19 while negative for HepPar-1 and AFP (not shown). H and E: Hematoxylin and eosin.