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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: J Diabetes. 2016 Oct 7;9(7):689–698. doi: 10.1111/1753-0407.12477

Table 3. Odds ratios (95% confidence intervals) of type 2 diabetes associated with tertile levels of plasma lipid measures in men and women separately.*.

T1 T2 T3 P for trend Per 1 SD increment
HDL-C
 Men
   Cases/controls 116/79 84/79 36/79
   OR (95% CI) 1.00 0.89 (0.54-1.47) 0.56 (0.29-1.05) 0.09 0.71 (0.53-0.94)
 Women
   Cases/controls 188/112 101/112 46/111
   OR (95% CI) 1.00 0.73 (0.44-1.19) 0.48 (0.26-0.88) 0.02 0.69 (0.53-0.90)
LDL-C
 Men
   Cases/controls 78/77 71/77 66/76
   OR (95% CI) 1.00 1.19 (0.65-2.15) 0.89 (0.46-2.15) 0.82 1.06 (0.83-1.36)
 Women
   Cases/controls 111/112 107/111 103/109
   OR (95% CI) 1.00 0.92 (0.53-1.61) 0.81 (0.49-1.34) 0.44 1.03 (0.84-1.27)
TG
 Men
   Cases/controls 46/79 69/79 121/78
   OR (95% CI) 1.00 1.09 (0.60-1.98) 2.25 (1.16-4.36) 0.007 1.61 (1.16-2.24)
 Women
   Cases/controls 42/115 86/111 207/109
   OR (95% CI) 1.00 1.82 (0.98-3.39) 5.03 (2.58-9.81) <0.001 1.85 (1.40-2.44)
TG/HDL-C ratio§
 Men
   Cases/controls 46/79 69/79 121/78
   OR (95% CI) 1.00 1.01 (0.53-1.90) 1.98 (1.04-3.79) 0.01 1.61 (1.12-2.34)
 Women
   Cases/controls 35/112 80/112 220/111
   OR (95% CI) 1.00 1.68 (0.87-3.26) 4.98 (2.48-10.0) <0.001 1.80 (1.34-2.39)

Abbreviations: OR, odds ratio; CI, confidence interval; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglycerides; TG/HDL-C ratio, the ratio of triglyceride to high-density lipoprotein cholesterol.

*

Multivariate model adjusted for age at blood taken (continuous), smoking (never, past, current smoker), alcohol intake (never, weekly or daily), physical activity (<0.5, 0.5-3.9, and ≥4 hours/week), education level (no, primary school, secondary or above), history of hypertension (yes, no), fasting status (yes, no), BMI (continuous), plasma concentrations of C-reactive protein (mmol/L) and adiponectin (μg/mL) (both in tertiles).

Linear trend was tested using the median level of each tertile of blood lipid profile.

P for interaction between TG and sex is 0.028.

§

P for interaction between TG/HDL and sex is 0.017.