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Changes in plaque area in low, intermediate and high time-averaged WSS sectors over six months. (a) Total plaque area. (b) VH-IVUS-derived plaque constituents. Sectors exposed to intermediate or high WSS were associated with a decrease in total plaque area, while sectors exposed to high WSS sectors demonstrated an increase in necrotic core and dense calcium. Error bars are 95% CIs. p < 0.05: low versus intermediate (*), intermediate versus high (#) and low versus high WSS (†).
