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. 2017 Mar 2;10:42. doi: 10.3389/fnmol.2017.00042

FIGURE 5.

FIGURE 5

PAR2-mediated LTD is protein kinase A (PKA)-dependent. (A) PAR2-agonist (10 μM AC55541) in presence of a PKA-inhibitor (2 μM KT5720) KT5720 (2 μM) fails to induce LTD. (B) Application of a protein kinase C (PKC) inhibitor (2 μM GF109203x) does not affect the induction of PAR2-mediated LTD. Averaged EPSP are plotted versus time. Representative traces at indicated times (a, b) are shown on top of each section.