Table 4.
Serum cytokine level during total knee arthroplasty.
| Control (N = 36) | RIPC (N = 36) | P | ||
|---|---|---|---|---|
| IL-6 | ||||
| Preop | 0.82 (0.80-1.15) | 0.81 (0.79-1.16) | 0.543 | |
| End TQ | 0.81 (0.79-1.11) | 0.87 (0.79-1.18) | 0.328 | |
| Post 1 h | 0.80 (0.78-1.15) | 0.81 (0.79-1.18) | 0.280 | |
| Post 6 h | 0.82 (0.80-1.06) | 0.83 (0.80-1.17) | 0.287 | |
| Post 24 h | 0.84 (0.82-1.03) | 0.85 (0.81-1.17) | 0.858 | |
| TNF-α | ||||
| Preop | 0.96 (0.51-1.20) | 1.14 (0.96-1.35) | 0.205 | |
| End TQ | 0.92 (0.45-1.25) | 1.10 (0.58-1.56) | 0.231 | |
| Post 1 h | 1.10 (0.64-1.40) | 1.15 (0.96-1.67) | 0.430 | |
| Post 6 h | 1.04 (0.59-1.25) | 1.06 (0.76-1.62) | 0.468 | |
| Post 24 h | 1.02 (0.51-1.17) | 1.05 (0.62-1.58) | 0.451 | |
| IL-10 | ||||
| Preop | 13.42 (8.67-15.71) | 10.71 (7.94-18.88) | 0.783 | |
| End TQ | 12.10 (7.61-15.09) | 11.79 (7.72-17.46) | 0.890 | |
| Post 1 h | 12.72 (8.14-15.04) | 10.99 (7.68-15.24) | 0.709 | |
| Post 6 h | 12.20 (7.79-15.58) | 10.98 (8.28-17.12) | 0.918 | |
| Post 24 h | 12.06 (8.28-15.17) | 10.70 (8.09-19.90) | 0.613 | |
| TGF-β | ||||
| Preop | 1.42 (1.05-2.23) | 1.47 (0.87-2.19) | 0.729 | |
| End TQ | 0.90 (0.67-1.96) | 0.92 (0.52-1.19) | 0.607 | |
| Post 1 h | 1.18 (0.77-2.33) | 0.97 (0.41-1.47) | 0.160 | |
| Post 6 h | 0.81 (0.39-1.22) | 0.85 (0.75-1.43) | 0.134 | |
| Post 24 h | 0.99 (0.58-1.21) | 0.68 (0.42-0.99) | 0.097 |
Values are expressed as median (25%-75%).
Abbreviations: Control, control group; RIPC, remote ischaemic preconditioning group; IL, interleukin; TNF-α, tumour necrosis factor-α; TGF-β, tumour growth factor-β; Preop, before anaesthesia induction; End TQ, just before release of tourniquet for operation site; Post 1 h, postoperative 1 h; Post 6 h, postoperative 6 h; Post 24 h, postoperative 24 h.