Table 3.
The odds ratios for developing adverse outcomes for each serum marker using MoM values with predefined cutoffs for upper and lower limits (no co-variates).
| P-CS | GDM | LGA | Low_ APGAR |
Macrosomia | PIH | Preterm | SGA | |
|---|---|---|---|---|---|---|---|---|
| Groups | 999 (12.9%) | 202 (63.9%) | 80 (4.4%) | 45 (5.3%) | 69 (5.1%) | 65 (4.2%) | 80 (5.1%) | 83 (2.9%) |
| AFP_MOM Lower (≤ 0.25) | 161119.37 (0.00 - Inf) | 0.00 (0.00 - Inf) | 0.00 (0.00 - Inf) | 0.00 (0.00 - Inf) | 0.00 (0.00 - Inf) | 0.00 (0.00 - Inf) | 0.00 (0.00 - Inf) | 0.00 (0.00 - Inf) |
| AFP_MOM Upper (≥ 2.0) | 0.82 (0.40 - 1.68) | 0.69 (0.21 - 2.29) | 0.59 (0.08 - 4.38) | 0.00 (0.00 - Inf) | 0.00 (0.00 - Inf) | 3.42 (1.16 - 10.07) $ | 0.61 (0.08 - 4.50) | 1.89 (0.56 - 6.34) |
| E3_MOM Lower (≤ 0.5) | 0.95 (0.41 - 2.18) | 1.00 (0.29 - 3.38) | 0.82 (0.11 - 6.12) | 3.24 (0.74 - 14.24) | 0.96 (0.13 - 7.23) | 1.04 (0.14 - 7.87) | 0.84 (0.11 - 6.30) | 0.78 (0.10 - 5.87) |
| E3_MOM Upper (≥ 2.0) | 1.62 (0.68 - 3.86) | 4.11 (1.85 - 9.11) $ | 2.35 (0.69 - 7.96) | 0.00 (0.00 - Inf) | 2.76 (0.81 - 9.41) | 3.00 (0.88 - 10.25) | 2.41 (0.71 - 8.19) | 0.69 (0.09 - 5.17) |
| HCG_MOM Lower (≤ 0.5) | 1.23 (0.81 - 1.86) | 0.80 (0.43 - 1.48) | 0.66 (0.24 - 1.85) | 0.29 (0.04 - 2.12) | 0.77 (0.27 - 2.15) | 0.44 (0.10 - 1.81) | 1.06 (0.45 - 2.51) | 0.88 (0.35 - 2.22) |
| HCG_MOM Upper (≥ 2.0) | 1.48 (1.00 - 2.21) | 0.92 (0.53 - 1.60) | 0.86 (0.37 - 2.02) | 0.50 (0.12 - 2.08) | 0.65 (0.23 - 1.82) | 1.77 (0.85 - 3.67) | 0.74 (0.29 - 1.88) | 1.38 (0.67 - 2.84) |
| Inhibin_MOM Lower (≤ 0.5) | 1.38 (0.73 - 2.61) | 0.65 (0.23 - 1.85) | 1.81 (0.63 - 5.23) | 0.68 (0.09 - 5.05) | 0.00 (0.00 - Inf) | 1.90 (0.56 - 6.39) | 1.85 (0.64 - 5.34) | 0.90 (0.21 - 3.81) |
| Inhibin_MOM Upper (≥2.0) | 1.28 (0.86 - 1.92) | 0.92 (0.51 - 1.64) | 1.01 (0.43 - 2.40) | 0.26 (0.04 - 1.90) | 0.94 (0.37 - 2.41) | 1.19 (0.46 - 3.09) | 0.85 (0.33 - 2.17) | 1.43 (0.66 - 3.07) |
| PAPPA_MOM Lower (≤ 0.4) | 1.24 (0.82 - 1.89) | 1.88 (1.14 - 3.10) $ | 0.62 (0.22 - 1.74) | 0.80 (0.24 - 2.67) | 0.72 (0.25 - 2.05) | 3.40 (1.64 - 7.03) $ | 1.31 (0.60 - 2.84) | 1.43 (0.66 - 3.12) |
| PAPPA_MOM Upper (≥ 2.5) | 0.92 (0.62 - 1.38) | 0.78 (0.41 - 1.51) | 0.77 (0.30 - 1.98) | 0.26 (0.04 - 1.92) | 0.53 (0.16 - 1.74) | 0.56 (0.13 - 2.39) | 0.15 (0.02 - 1.11) | 1.42 (0.65 - 3.09) |
$: P<0.05; P-CS: primary caesarian section; GDM: gestational diabetes mellitus; LGA: large for gestational age; SGA: small for gestational age; PIH: pregnancy-induced hypertension.