Table 1.
All patients | |||||
---|---|---|---|---|---|
Variable | Total | Right-side colon | Left-side colon | Rectum | P-value, chi-square |
Number of patients | 984 | 300 | 345 | 339 | |
Age | |||||
≤50 y | 387 | 120 | 138 | 129 | 0.934 |
51-65 y | 387 | 120 | 131 | 136 | |
>65 y | 210 | 60 | 76 | 74 | |
Gender | |||||
Male | 637 | 177 | 228 | 203 | 0.036 |
Female | 347 | 123 | 117 | 107 | |
Mucinous histology | |||||
Yes | 158 | 69 | 49 | 40 | <0.001 |
No | 826 | 231 | 296 | 299 | |
Stage at diagnosis | |||||
I | 8 | 1 | 2 | 5 | <0.001 |
II | 70 | 20 | 20 | 30 | |
III | 206 | 48 | 56 | 102 | |
IV | 700 | 231 | 267 | 202 | |
First line therapy | |||||
Chemotherapy | 740 | 222 | 259 | 259 | 0.685 |
Bevacizumab + chemotherapy | 244 | 78 | 86 | 80 | |
Metastatic organ | |||||
1 | 714 | 221 | 251 | 242 | 0.808 |
>1 | 270 | 79 | 94 | 97 | |
CEA | |||||
≤5 ng/ml | 275 | 81 | 92 | 102 | 0.563 |
>5 ng/ml | 702 | 217 | 250 | 235 | |
unknown | 7 | 2 | 3 | 2 | |
LDH | |||||
≤245 U/ml | 702 | 228 | 230 | 244 | 0.035 |
>245 U/ml | 279 | 71 | 113 | 95 | |
unknown | 3 | 1 | 2 | ||
Backbone chemotherapy | |||||
Oxaliplatin-based | 682 | 213 | 244 | 225 | 0.685 |
Irinotecan-based | 257 | 73 | 87 | 97 | |
5-fluorouracil only | 45 | 14 | 14 | 17 | |
Bevacizumab beyond first line | |||||
Yes | 83 | 26 | 31 | 26 | 0.813 |
No | 901 | 274 | 314 | 313 | |
Cetuximab treated | |||||
Yes | 104 | 29 | 40 | 35 | 0.637 |
No | 880 | 271 | 304 | 304 | |
Primary tumor resection | |||||
Yes | 606 | 186 | 220 | 200 | 0.432 |
No | 378 | 114 | 125 | 139 |