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. 2017 Feb 15;7(2):20. doi: 10.3390/brainsci7020020

Table 24.

GHK and Genes Associated with Dendrites.

UP Gene Title Percent Change
1 potassium voltage-gated channel, Shal-related subfamily, member 1, KCND1 845
2 contactin associated protein-like 2, CNTNAP2 581
3 leukocyte specific transcript 1, LST1 395
4 gamma-aminobutyric acid (GABA) A receptor, alpha 5 /// gamma-aminobutyric acid receptor subunit alpha-5-like, GABRA5 /// LOC100509612 392
5 chemokine (C-C motif) ligand 19, CCL19 378
6 doublecortin-like kinase 1, DCLK1 365
7 p21 protein (Cdc42/Rac)-activated kinase 1, PAK1 363
8 potassium voltage-gated channel, Shaw-related subfamily, member 3, KCNC3 332
9 EPH receptor B1, EPHB1 330
10 gamma-aminobutyric acid (GABA) B receptor, 1 /// ubiquitin D, GABBR1 /// UBD 310
11 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, CACNA1A 286
12 nephroblastoma overexpressed gene, NOV 275
13 obscurin-like 1, OBSL1 263
14 neuroligin 1, NLGN1 261
15 low density lipoprotein receptor-related protein 1, LRP1 249
16 glutamate receptor, ionotropic, kainate 3, GRIK3 246
17 RNA binding protein, fox-1 homolog (C. elegans) 2, RBFOX2 245
18 glutamate receptor, metabotropic 1, GRM1 231
19 glutamate receptor interacting protein 1, GRIP1 230
20 glutamate receptor, ionotropic, N-methyl d-aspartate 1, GRIN1 216
21 MCF.2 cell line derived transforming sequence, MCF2 202
22 purinergic receptor P2X, ligand-gated ion channel, 4, P2RX4 180
23 synapsin I, SYN1 170
24 Abl-interactor 2, ABI2 168
25 calcium channel, voltage-dependent, L type, alpha 1F subunit, CACNA1F 168
26 membrane associated guanylate kinase, WW and PDZ domain containing 2, MAGI2 155
27 ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast), UBE2I 150
28 nuclear mitotic apparatus protein 1, NUMA1 147
29 glutamate receptor, ionotropic, N-methyl d-aspartate 2C, GRIN2C 146
30 probable transcription factor PML-like /// promyelocytic leukemia, LOC652346 /// PML 144
31 fasciculation and elongation protein zeta 1 (zygin I), FEZ1 143
32 glutamate receptor, metabotropic 7, GRM7 140
33 acetylcholinesterase, ACHE 131
34 retinoic acid receptor, alpha, RARA 123
35 misshapen-like kinase 1, MINK1 119
36 kelch-like 1 (Drosophila), KLHL1 119
37 neuralized homolog (Drosophila), NEURL 115
38 protein kinase C, gamma, PRKCG 106
39 drebrin 1, DBN1 103
40 neurofibromin 1, NF1 102
DOWN Gene Title Percent Change
1 bassoon (presynaptic cytomatrix protein), BSN −563
2 membrane metallo-endopeptidase, MME −540
3 adenylate cyclase 10 (soluble), ADCY10 −460
4 discs, large homolog 4 (Drosophila), DLG4 −452
5 Kv channel interacting protein 1, KCNIP1 −413
6 EPH receptor A7, EPHA7 −365
7 PTK2B protein tyrosine kinase 2 beta, PTK2B −348
8 sterile alpha motif domain containing 4A, SAMD4A −315
9 dopamine receptor D4, DRD4 −296
10 FEZ family zinc finger 2, FEZF2 −295
11 calcium channel, voltage-dependent, N type, alpha 1B subunit, CACNA1B −290
12 mitogen-activated protein kinase 8 interacting protein 1, MAPK8IP1 −289
13 regulator of G-protein signaling 11, RGS11 −266
14 cyclin-dependent kinase 5, regulatory subunit 1 (p35), CDK5R1 −260
15 glutamate receptor, ionotropic, kainate 1, GRIK1 −254
16 thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian), THRA −253
17 cyclic nucleotide gated channel alpha 3, CNGA3 −249
18 adenylate cyclase 2 (brain), ADCY2 −247
19 proprotein convertase subtilisin/kexin type 2, PCSK2 −242
20 Rho guanine nucleotide exchange factor (GEF) 15, ARHGEF15 −230
21 potassium voltage-gated channel, Shal-related subfamily, member 3, KCND3 −224
22 protein tyrosine phosphatase, receptor type, D, PTPRD −221
23 cytochrome b-245, beta polypeptide, CYBB −217
24 GABA(A) receptors associated protein like 3, pseudogene, GABARAPL3 −197
25 neutrophil cytosolic factor 1C pseudogene, NCF1C −196
26 promyelocytic leukemia, PML −196
27 C-reactive protein, pentraxin-related, CRP −182
28 glutamate receptor, ionotropic, N-methyl d-aspartate 2A, GRIN2A −180
29 tubby like protein 1, TULP1 −176
30 Mitogen-activated protein kinase 8 interacting protein 3, MAPK8IP3 −174
31 cell adhesion molecule with homology to L1CAM (close homolog of L1), CHL1 −171
32 choline O-acetyltransferase, CHAT −160
33 glutamate receptor, ionotropic, kainate 5, GRIK5 −159
34 glutamate receptor, ionotropic, kainate 4, GRIK4 −155
35 5-hydroxytryptamine (serotonin) receptor 6, HTR6 −150
36 tachykinin receptor 3, TACR3 −150
37 5-hydroxytryptamine (serotonin) receptor 5A, HTR5A −149
38 protease, serine, 12 (neurotrypsin, motopsin), PRSS12 −141
39 cholinergic receptor, nicotinic, alpha 4, CHRNA4 −139
40 5-hydroxytryptamine (serotonin) receptor 2A, HTR2A −135
41 leucine zipper, putative tumor suppressor 1, LZTS1 −130
42 neuroligin 4, X-linked, NLGN4X −128
43 glutamate receptor, ionotrophic, AMPA 3, GRIA3 −126
44 glutamate receptor, metabotropic 6, GRM6 −120
45 paralemmin, PALM −115
46 copine VI (neuronal), CPNE6 −114
47 cytoplasmic polyadenylation element binding protein 3, CPEB3 −112
48 corticotropin releasing hormone receptor 1, CRHR1 −109
49 doublecortin, DCX −108
50 regulator of G-protein signaling 14, RGS14 −108
51 apolipoprotein E, APOE −107
52 calcium binding protein 1, CABP1 −106
53 mitogen-activated protein kinase 8 interacting protein 2, MAPK8IP2 −103
54 neurochondrin, NCDN −102