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. 2017 Feb 15;7(2):20. doi: 10.3390/brainsci7020020

Table 28.

GHK and Gene Associate with Sensory Nerve Cells.

UP Gene Title Percent Change
1 opioid receptor, mu 1, OPRM1 1294
2 T-box 1, TBX1 553
3 adrenergic, beta-1-, receptor, ADRB1 477
4 gamma-aminobutyric acid (GABA) A receptor, alpha 5 /// gamma-aminobutyric acid receptor subunit alpha-5-like, GABRA5 /// LOC100509612 392
5 calcium channel, voltage-dependent, L type, alpha 1D subunit, CACNA1D 372
6 olfactory receptor, family 2, subfamily W, member 1, OR2W1 370
7 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type, GNAL 366
8 olfactory receptor, family 2, subfamily B, member 6, OR2B6 345
9 cyclic nucleotide gated channel beta 1, CNGB1 330
10 EPH receptor B1, EPHB1 330
11 inositol 1,4,5-triphosphate receptor, type 3, ITPR3 298
12 olfactory receptor, family 7, subfamily A, member 17, OR7A17 285
13 nuclear factor I/B, NFIB 279
14 islet amyloid polypeptide, IAPP 276
15 opiate receptor-like 1, OPRL1 246
16 potassium voltage-gated channel, KQT-like subfamily, member 4, KCNQ4 245
17 myosin, heavy chain 14, non-muscle, MYH14 243
18 taste receptor, type 2, member 13, TAS2R13 237
19 olfactory receptor, family 2, subfamily F, member 2, OR2F2 232
20 glutamate receptor, metabotropic 1, GRM1 231
21 chemokine (C-C motif) ligand 3 /// chemokine (C-C motif) ligand 3-like 1 /// chemokine (C-C motif) ligand 3-like 3, CCL3 /// CCL3L1 /// CCL3L3 228
22 polycystic kidney disease 2-like 1, PKD2L1 225
23 glutamate receptor, ionotropic, N-methyl d-aspartate 1, GRIN1 216
24 adenylate cyclase activating polypeptide 1 (pituitary), ADCYAP1 215
25 ATPase, Ca++ transporting, plasma membrane 2, ATP2B2 214
26 olfactory receptor, family 7, subfamily C, member 1, OR7C1 207
27 purinergic receptor P2X, ligand-gated ion channel, 3, P2RX3 207
28 neuropeptide Y receptor Y1, NPY1R 201
29 family with sequence similarity 38, member B, FAM38B 193
30 olfactory receptor, family 1, subfamily A, member 1, OR1A1 189
31 taste receptor, type 2, member 14, TAS2R14 181
32 purinergic receptor P2X, ligand-gated ion channel, 4, P2RX4 180
33 receptor accessory protein 2, REEP2 174
34 endothelin receptor type A, EDNRA 173
35 cannabinoid receptor 1 (brain), CNR1 172
36 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor), MC1R 164
37 olfactory receptor, family 12, subfamily D, member 3 /// olfactory receptor, family 5, subfamily V, member 1, OR12D3 /// OR5V1 163
38 odorant binding protein 2A /// odorant binding protein 2B, OBP2A /// OBP2B 162
39 prepronociceptin, PNOC 150
40 phospholipase C, beta 2, PLCB2 148
41 glutamate receptor, metabotropic 7, GRM7 140
42 oxytocin, prepropeptide, OXT 136
43 WD repeat domain 1, WDR1 127
44 olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene) /// olfactory receptor, family 1, subfamily D, member 5, OR1D4 /// OR1D5 125
45 UDP glucuronosyltransferase 2 family, polypeptide A1 /// UDP glucuronosyltransferase 2 family, polypeptide A2, UGT2A1 /// UGT2A2 121
46 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), PTGS2 120
47 taste receptor, type 2, member 4, TAS2R4 118
48 lysozyme, LYZ 111
49 protein kinase C, gamma, PRKCG 106
50 collagen, type XI, alpha 1, COL11A1 103
51 POU class 4 homeobox 3, POU4F3 102
52 nuclear receptor subfamily 2, group F, member 6, NR2F6 100
DOWN Gene Title Percent Change
1 taste receptor, type 2, member 9, TAS2R9 −1494
2 endothelin receptor type B, EDNRB −768
3 necdin homolog (mouse), NDN −729
4 membrane metallo-endopeptidase, MME −540
5 EPH receptor A3, EPHA3 −485
6 arachidonate lipoxygenase 3, ALOXE3 −461
7 bradykinin receptor B1, BDKRB1 −426
8 gap junction protein, beta 4, 30.3kDa, GJB4 −317
9 nerve growth factor (beta polypeptide), NGF −243
10 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1, GNAT1 −242
11 olfactory receptor, family 3, subfamily A, member 1, OR3A1 −234
12 apelin receptor, APLNR −230
13 olfactory receptor, family 2, subfamily F, member 1 /// olfactory receptor, family 2, subfamily F, member 2, OR2F1 /// OR2F2 −212
14 olfactory receptor, family 12, subfamily D, member 3, OR12D3 −201
15 olfactory receptor, family 6, subfamily A, member 2, OR6A2 −199
16 cholecystokinin B receptor, CCKBR −198
17 carbonic anhydrase VI, CA6 −192
18 olfactory receptor, family 5, subfamily I, member 1, OR5I1 −191
19 collagen, type XI, alpha 2, COL11A2 −186
20 olfactory receptor, family 10, subfamily H, member 3, OR10H3 −182
21 glutamate receptor, ionotropic, N-methyl D-aspartate 2A, GRIN2A −180
22 protein phosphatase, EF-hand calcium binding domain 2, PPEF2 −178
23 sodium channel, nonvoltage-gated 1 alpha, SCNN1A −175
24 trace amine associated receptor 5, TAAR5 −168
25 gastric inhibitory polypeptide, GIP −164
26 olfactory receptor, family 2, subfamily H, member 1, OR2H1 −156
27 olfactory receptor, family 2, subfamily J, member 2, OR2J2 −155
28 otoferlin, OTOF −155
29 discs, large homolog 2 (Drosophila), DLG2 −142
30 cholinergic receptor, nicotinic, alpha 4, CHRNA4 −139
31 5-hydroxytryptamine (serotonin) receptor 2A, HTR2A −135
32 tectorin alpha, TECTA −126
33 sodium channel, voltage-gated, type XI, alpha subunit, SCN11A −124
34 olfactory receptor, family 7, subfamily C, member 2, OR7C2 −120
35 taste receptor, type 2, member 16, TAS2R16 −120
36 glutamate receptor, metabotropic 6, GRM6 −120
37 opioid receptor, kappa 1, OPRK1 −119
38 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1, ATP6V1B1 −118
39 olfactory marker protein, OMP −118
40 contactin 5, CNTN5 −116
41 cysteinyl leukotriene receptor 2, CYSLTR2 −113
42 olfactory receptor, family 2, subfamily H, member 2, OR2H2 −110
43 rhodopsin, RHO −108
44 interleukin 10, IL10 −107
45 olfactory receptor, family 11, subfamily A, member 1, OR11A1 −107
46 polymeric immunoglobulin receptor, PIGR −107
47 guanine nucleotide binding protein (G protein), gamma 13, GNG13 −106
48 tubby homolog (mouse), TUB −101
49 glutamate receptor, metabotropic 8, GRM8 −101
50 cystatin S, CST4 −101