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. 2017 Jan 26;8(2):50. doi: 10.3390/genes8020050

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Bacterial isolates that encode for a RyfA1-like molecule are enteropathogens. All bacterial isolates whose genome is sequenced and available on the National Center for Biotechnology Information (NCBI) [21], were evaluated for the presence of ryfA. Next all identified species were grouped based on the similarity of nucleic acid sequence within the ryfA five-nucleotide variable region. Four different iterations of the variable region were found, TGTTT, CGCGT, CCCCC, and CACCC. Three of the four variable region iterations contained higher GC content and were termed “ryfA1-like”. The number of isolates containing each RyfA iteration as well as the number of those with each group that are pathogenic are indicated.