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. 2017 Mar 2;7:43683. doi: 10.1038/srep43683

Figure 4. RNF7 knockdown induced higher percentage of DU145 and PC3 cell death to chemotherapeutic agent cisplatin treatment.

Figure 4

Cells transfected with shRNF7-2 (shRNF7-2 group) or shCON (shCON group) were treated with cisplatin. Untreated cells served as negative controls. Cell apoptosis was detected by Annexin V and PI staining. (a) Representative results of Annexin V and PI staining; (b) Statistical analysis of cell apoptosis. Live: Annexin V and PI double negative cells. Ann+: Annexin V positive but PI negative cells. Ann+ PI+: Annexin V and PI double positive cells. PI+: PI positive but Annexin V negative cells. Data were mean ± SD. ***P < 0.001.