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. 2017 Mar 2;7:43509. doi: 10.1038/srep43509

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Copyright © 2017, The Author(s)

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(A) Representative images of H&E-stained retinas. Asterisk (_*) indicates cystoid edema. Scale bar = 50 μm. Cystoid edema was observed 1 day after photocoagulation in the INL and ONL. Plots below illustrate quantitative INL (B) and ONL (C) thickness data. The thickness of the INL was dramatically increased 1 day after occlusion, gradually recovering in a time-dependent manner. ONL thickness was significantly decreased on day 7, and there was no change on days 1 and 3. The data are expressed as means ± S.E.M. (n = 3–7). ^##P < 0.01, ^#P < 0.05 vs. untreated control (Dunnett’s test). INL; inner nuclear layer; ONL; outer nuclear layer. (D) The incidence of retinal detachment (arrow) was approximately 90.9% (20/22).