Table 1. Ingenuity Pathway Analysis.

Function annotation	p-value		Number of molecules
Abnormal muscle morphology	1.03E-04		24
Mitochondrial quantity	4.80E-04		7
Muscle mass	8.22E-04		17
Muscle function	8.67E-04		23
Oxidation of fatty acids	2.92E-03		7
Pathway annotation
Oxidative phosphorylation	2.71E-14		38
Mitochondrial dysfunction	2.71E-11		45
Regulation	z-score	Direction	Number of molecules
Oxidation of fatty acids	2.20	Down	7

Upper part: The top-five annotated functions sorted by p-values and number of associated genes. Middle part: The top-tow annotated pathways sorted by p-values and number. Lower part: Gene transcripts annotated with oxidation of fatty acids were significantly down-regulated in T2D patients.