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. 2017 Mar 2;7:43522. doi: 10.1038/srep43522

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) Principal coordinate analysis plot generated using a weighted UniFrac metric. The two components explained 69.7% of the variance. (b) Weighted UniFrac distance metric in the HFD-fed control, the BlaG-treated, and the BloJ-treated groups. (c) Bacterial composition at the genus level in the samples. For genus-level assignment of 16 S reads (16 S rRNA gene V1–V2 region), a 94% sequence identity threshold was applied. The vertical axis represents the relative abundance (%) of each genus in the microbiota. (d) The number of Bifidobacterium in caecal samples quantified by quantitative polymerase chain reaction. Data represent the mean ± SEM. Tukey–Kramer multiple comparison test was used. Different letters next to bars indicate a significant difference (P < 0.05).