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. 2017 Jan 27;18(Suppl 1):1–9. doi: 10.1186/s12859-016-1427-5

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — PAI calculation. Part of the taxonomic tree illustrating the PAI calculation. For gene 1, the only ortholog gene was found in Bonobo (gene 2). It means the evolutionary age of gene1 and gene 2 is 13 (“Hominidae” – young genes). Contrariwise, for gene 3 we found ortholog even in opossum (gene 4). It means that genes diverged on Mammalia stage, so the PAI is equal to 7 (“Mammalia” – “moderate age” genes)