Skip to main content
. 2017 Jan 3;11(2):1142–1164. doi: 10.1021/acsnano.6b05737

Figure 2.

Figure 2

RNA modifications to impact the stability of RNA nanoparticles. (A) Modification to RNA’s sugar moiety. Reprinted with permission from ref (78). Copyright 2008 Elsevier. (B) Backbone modifications. Reprinted with permission from ref (78). Copyright 2008 Elsevier. (C) Synthetic RNA triplex to replace native duplex without compromising original function. Reprinted from ref (85). Copyright 2015 American Chemical Society. (D) Tm changes of RNA nanoparticles resulted from 2′ alteration. Reprinted from ref (22). Copyright 2014 American Chemical Society. (E) The 2′ alteration resulted in different levels of serum stability. Reprinted from ref (22). Copyright 2014 American Chemical Society.