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. 2017 Jan 3;11(2):1142–1164. doi: 10.1021/acsnano.6b05737

Figure 7.

Figure 7

RNA nanoparticles for immunotherapy and chemotherapeutic delivery. (A) RNA nanoparticles display little to no immune response under normal conditions, but addition of immunostimulatory CpG sequences results in huge increases in the immune response for cytokine production. Reprinted with permission from ref (21). Copyright 2014 Oxford University Press. (B) Methods for conjugation of chemicals and drugs to RNA nanoparticles. Reprinted with permission from ref (119). Copyright 2014 Elsevier.