Figure 2:

Model performance evaluated at different sets of quality metric (validation set sensitivity and specificity) thresholds. Three panels show percent decisive decisions, sensitivity and specificity on the testing set. Each square shows the performance of the pipeline under a particular threshold setting. The color of the square (different shades of red) represents the performance, with red mapped to the best performance. Black dashed line encloses threshold region where the model makes decisive decision for more than 60% of the individuals. The most stringent threshold settings (top right corner of individual panel) did not result in any decisive decisions. These results were left blank in the figure.