Table 5.

Most prominent deregulated mRNA targets in obstructive nephropathy

Gene symbol Description	FC	p-value	let-7a-5p	miR-125b-5p	miR-16-5p	miR-26a-5p	miR- 29b-3p
Dtx4
E3 ubiquitin-protein ligase or deltex 4 homolog (Drosophila)	2,41	0,001	√	√
Lmod1
Leiomodin 1 (smooth muscle)	1,57	0,001		√	√
Adamts19
A disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19	2,97	0,0006				√	√
Nav1
Neuron navigator 1	1,57	0,002				√	√

FC fold change