Table 1.
Glycemic status and prevalence of metabolic syndrome according to family history of diabetes in first-degree relatives
| Total (n = 2059) | Men (n = 876) | Women (n = 1183) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| FH− | FH+ | P | FH− | FH+ | P | FH− | FH+ | P | |
| (n = 1570) | (n = 489) | (n = 655) | (n = 221) | (n = 915) | (n = 268) | ||||
| Glycemic status | |||||||||
| NGT | 1358 (86.5%) | 386 (78.9%) | <0.001 | 533 (81.4%) | 158 (71.5%) | <0.001 | 825 (90.2%) | 228 (85.1%) | 0.019 |
| IFG | 184 (11.7%) | 70 (14.3%) | 111 (16.9%) | 42 (19.0%) | 73 (8.0%) | 28 (10.4%) | |||
| Diabetes | 28 (1.8%) | 33 (6.7%) | 11 (1.7%) | 21 (9.5%) | 17 (1.9%) | 12 (4.5%) | |||
| Prevalence of metabolic syndrome | 190 (12.1%) | 104 (21.3%) | <0.001 | 123 (18.8%) | 74 (33.5%) | <0.001 | 67 (7.3%) | 30 (11.2%) | 0.042 |
| Waist circumference (>90 cm in men and >80 cm in women) | 344 (22.1%) | 131 (26.9%) | 0.029 | 144 (22.1%) | 58 (26.5%) | 0.186 | 200 (22.1%) | 73 (27.2%) | 0.082 |
| Triglycerides (≥150 mg/dL or medication use) | 323 (20.6%) | 146 (29.9%) | <0.001 | 236 (36.1%) | 105 (47.5%) | 0.003 | 87 (9.5%) | 41 (15.3%) | 0.010 |
| HDL cholesterol (<40 mg/dL in men and <50 mg/dL in women or medication use) | 583 (37.2%) | 200 (40.9%) | 0.142 | 205 (31.3%) | 83 (37.6%) | 0.089 | 378 (41.4%) | 117 (43.7%) | 0.511 |
| Blood pressure (≥130/85 mmHg or antihypertensive medication use) | 222 (14.1%) | 100 (20.4%) | 0.001 | 162 (24.7%) | 83 (37.6%) | <0.001 | 60 (6.6%) | 17 (6.3%) | 0.901 |
| Fasting glucose (≥100 mg/dL or medication use) | 212 (13.5%) | 103 (21.1%) | <0.001 | 122 (18.6%) | 63 (28.5%) | 0.002 | 90 (9.8%) | 40 (14.9%) | 0.019 |
Statistical significance was defined as a P value of <0.05 (Italic values)
FH family history of diabetes, IFG impaired fasting glucose, NGT normal glucose tolerance
P values are from χ2-test