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. 2017 Mar 1;15:18. doi: 10.1186/s12951-017-0251-z

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Cytotoxicity and biological toxicity induced by Chit-DC and Chit-DC-VB12. a CCK-8 cytotoxicity assay was performed in Caco-2 cells. The results are shown as the mean ± SD for three independent trials. b Zebra fish embryo development under standard/healthy conditions (hpf = hours post-fertilization). c Zebra fish embryo development after 24, 48, 72, 96 hpf of incubation with different concentrations of Chit-DC and Chit-DC-VB12