Table 2.

Risk of incident type 2 diabetes mellitus (T2DM) by quartiles of TyG and TyG-D

	Quartile 1	Quartile 2	Quartile 3	Quartile 4	P trend
TyG
Range	<8.16	8.16 to 8.47	8.48 to 8.81	≥8.82
No. of cases	18	35	52	88
No. of person-years	8740.50	8526.83	8529.25	8399.50
Incidence ratea	2.06	4.10	6.10	10.48	<0.001
Unadjusted model	1 (ref)	2.36 (1.33–4.16)	3.58 (2.09–6.12)	6.30 (3.78–10.50)	<0.001
Multivariable adjusted model 1b	1 (ref)	2.38 (1.17–4.85)	3.71 (1.89–7.29)	5.54 (2.87–10.71)	<0.001
Multivariable adjusted model 2c	1 (ref)	2.49 (1.22–5.08)	3.89 (1.98–7.65)	5.69 (2.94–11.01)	<0.001
Multivariable adjusted model 3d	1 (ref)	2.48 (1.20–5.11)	3.77 (1.83–7.79)	5.30 (2.21–12.71)	<0.001
TyG-D
Range	<−0.27	−0.27 to 0	0.01 to 0.31	≥0.32
No. of cases	41	39	30	83
No. of person-years	8520.00	9747.08	7373.00	8556.00
Incidence ratea	4.81	4.00	4.07	9.70	<0.001
Unadjusted model	1 (ref)	0.95 (0.58–1.55)	1.15 (0.68–1.93)	2.19 (1.41–3.39)	<0.001
Multivariable adjusted model 1b	1 (ref)	0.92 (0.52–1.63)	1.09 (0.59–2.03)	2.51 (1.50–4.19)	<0.001
Multivariable adjusted model 2c	1 (ref)	0.92 (0.52–1.64)	1.10 (0.59–2.05)	2.52 (1.51–4.22)	<0.001
Multivariable adjusted model 3d	1 (ref)	1.14 (0.63–2.09)	1.54 (0.80–2.99)	3.91 (2.22–6.87)	<0.001

Data are hazard ratios (HRs) and 95% confidence intervals (95% CIs)

TyG triglyceride glucose index, TyG-D difference in TyG value at the end of follow-up minus that at baseline

^aPer 1000 person-years

^bAdjusted for gender, age, family history of diabetes and WC

^cAdjusted for variables in ^b as well as education level, marital status, smoking, alcohol consumption and physical activity

^dAdjusted for variables in ^c as well as SBP, DBP and TC, HDL-C and LDL-C levels