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. 2017 Mar 1;17:182. doi: 10.1186/s12879-017-2287-y

Table 1.

Characteristics of patients with HBV reactivation during or after DAA treatment for HCV published in literature

Patient Ref. Gender, age HCV genotype Previous IFN DAA treatment HBV profile HIV status Symptoms onset
1 [7] M, 53 4d Yes SOF/LDV Resolved HBV + At 6 weeks during DAA
2 [6] M, 55 1a Yes SOF/SMV Inactive HBV - At 8 weeks during DAA
3 [6] M, 57 1a Yes SOF/SMV Occult HBV - At 4 weeks during DAA
4 [10] F, 59 1b Yes SOF/SMV/RBV Resolved HBV - At 11 weeks during DAA
5 [9] M, 69 1b No DCV/ASV Inactive HBV - At 6 weeks during DAA
6 [8] F, 83 1b NA DCV/ASV NA (HBsAg neg) - At 20 weeks after DAA

Legend: M male, F female, IFN interferon, RBV ribavirin, SOF sofosbuvir, SMV simeprevir, DCV daclatasvir, ASV asunaprevir, HBV hepatitis B virus, HCV hepatitis C virus, DAA direct antiviral agents, NA not available, neg negative