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. 2017 Mar 1;17:183. doi: 10.1186/s12879-017-2284-1

Table 1.

Study definitions

Terms Definitions
Clinical cure Resolution of or improvement in the index infection without need for further antibiotic therapy
Microbiological eradication At least one negative culture of an index pathogen from a clinical specimen that was obtained during or after the course of antibiotic therapy
Superimposed infection New onset of infection caused by any pathogens other than ESBL-producing Enterobacteriaceae during the course of antibiotic therapy
28-day mortality Death from any cause within 28 days after enrollment