Table 4.
Published reports of UESL (N > 3) from 1987 to 2014. Follow‐up and outcome of patients who had surgical resection only, as well as combined therapy, are outlined
| Surgical excision Only | Combined therapy | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Author, publication year | No. of patients | Age range, years | Gender (M/F) | No. of patients | Follow–up, months | Alive | No. of patients | Follow–up, months | Alive |
| Techavichit et al., 201620 | 6 | 5–22 | 3/3 | 0 | – | – | 5 | 10–133 | 4/5a |
| Cao et al., 201425 | 9 | 6–37 | 6/3 | 1 | 34 | 0/1 | 8 | 5–76 | 7/8 |
| Walther et al., 201421 | 6 | 7–13 | 4/2 | 1 (1 OLT)b | 84 | 1/1 | 5 (2 OLT) | 12–48 | 5/5 |
| Plant et al., 201335 | 5 | 10–19 | 4/1 | 0 | – | – | 5 (1 OLT) | 21–68 | 5/5 |
| Ismail et al., 201323 | 10 | 4 months to 17 | 8/2 | 0 | – | – | 10 (1 OLT)c | 50–222 | 9/10 |
| Upadhyaya et al., 201024 | 11 | 4 months to 15 | – | 1 | NR | 1/1 | 10 | – | 7/10 |
| Weitz et al., 200713 | 5 | – | – | – | – | – | – | – | d |
| Bisogno et al., 20025 | 17 | 4 months to 16 | 10/7 | 1 | NR | 0/1e | 15 | 14–240 | 12/15f |
| Kim et al., 200214 | 6 | 7–13 | 4/2 | 0 | – | – | 6 | 22–108 | 5/6 |
| Webber et al., 19993 | 7 | 2–12 | 4/3 | 0 | – | – | 7 | 6–150 | 4/7 |
| Urban et al., 199328 | 4 | 6–13 | 0/4 | 0 | – | – | 4 | 22–79 | 4/4 |
| Walker et al., 199218 | 4 | 7–29 | 2/2 | 2 | 18–240 | 2/2 | 2 | 13–30 | 1/2 |
| Lack et al., 199119 | 16 | 2–21 | 10/6 | 7 | 4–12 | 0/7 | 9 | 4–60 | 3/9 |
| Leuschner et al., 199026 | 9 | 4–20 | 5/4 | 5 | 3–24 | 2/4g | 3 | 15–59 | 3/3 |
| Newman et al., 198927 | 4 | 5–13 | 2/2 | 0 | – | – | 4 | – | 2/4 |
| Horowitz et al., 198712 | 5 | 4–16 | 4/1 | 1 | 6 | 0/1 | 4 | 12–58 | 2/4 |
NR, not reported; OLT, orthotopic liver transplant.
One patient underwent chemotherapy only. The deceased patient from the combined therapy group had an incomplete resection.
This patient underwent OLT without adjuvant chemotherapy due to local recurrence after prior resection with neoadjuvant and adjuvant chemotherapy.
The deceased patient was initially diagnosed with hepatoblastoma and died 4 months posttransplant of postoperative complications.
All patients with embryonal sarcomas of the liver underwent surgical resection with negative margins, however the use of chemotherapy could not be ascertained. The overall survival of UESL patients in this study was 80% (4/5).
Postsurgical death. The patient also had chemotherapy alone and died 1.8 years after diagnosis.
One patient died of unrelated trauma.
One patient had no outcome reported.