Table 1.
Purification of prothrombin by anion exchange or VHH affinity chromatography.
| Parameter | Units | CCCB | QFF | VHH affinity |
|---|---|---|---|---|
| HCP | ng/mg | 1,453,955 | 19,336 | 3,109 |
| AEC‐HPLC pre‐peak | % | – | 30.5 | 7.5 |
| SEC‐HPLC monomer | % | – | 94.9 | 97.6 |
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