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. 2017 Feb 24;12:182–190. doi: 10.1016/j.redox.2017.02.013

Table 1.

Sterol distribution in cultured fibroblasts after 6 days incubation with 1 μM a-Lan.a

Alkynyl sterols
Natural sterols
a-Lan a-Lath a-7-DHC a-Chol Lan Lath 7-DHC Chol
Control 0.055±0.013 n.d. 0.051±0.017 0.660±0.085 0.021±0.003 n.d. 0.042±0.008 12.7±0.8
fibroblast
SLOS 0.143±0.021 n.d. 0.657±0.096 n.d. 0.015±0.001 0.167±0.145 3.47±0.51 8.1±1.7
fibroblast
NPC 0.090±0.05 n.d. 0.011±0.011 1.308±0.22 0.017±0.002 0.051±0.089 0.049±0.016 33.9±6.9
fibroblast
a

nmol of sterol determined by HPLC-MS and GC per 106 cells. Data presented are averages determined from triplicate analyses. n.d., not detected.