Table 1.
Serum Biochemical Analysis at Delivery
| Obese controls | Non-GDM | GDM | P | |
|---|---|---|---|---|
| Total cholesterol (mg/dL) | 188.9 ± 29.7 | 198.6 ± 21.7 | 200.6 ± 27.7 | 0.68 |
| HDL (mg/dL) | 58.6 ± 17.4 | 56.4 ± 8.0 | 61.0 ± 11.9 | 0.81 |
| Triglycerides (mg/dL) | 148.4 ± 53.3 | 231.4 ± 29.0* | 254.1 ± 62.3*,# | 0.002 |
| LDL (mg/dL) | 108.6 ± 20.5 | 95.9 ± 28.3 | 88.7 ± 21.5 | 0.31 |
| VLDL (mg/dL) | 39.7 ± 22.4 | 46.3 ± 5.9 | 50.9 ± 12.5 | 0.95 |
| Adiponectin (μg/mL) | 7.6 ± 3.4 | 9.6 ± 6.8 | 9.4 ± 7.0 | 0.8 |
| Resistin (ng/mL) | 182.7 ± 80.3 | 145.9 ± 32.3 | 144.2 ± 60.3 | 0.46 |
| PAI-1 (ng/mL) | 39.8 ± 32.1 | 31.5 ± 21.0 | 17.7 ± 6.2 | 0.26 |
| Leptin (ng/mL) | 20.7 ± 7.9 | 56.8 ± 22.5* | 46.7 ± 19.1# | 0.004 |
| IL-6 (pg/mL) | 4.6 ± 8.1 | 2.6 ± 1.7 | 3.1 ± 1.1 | 0.75 |
| IL-8 (pg/mL) | 3.0 ± 1.9 | 1.7 ± 0.6 | 2.2 ± 0.7 | 0.21 |
| TNF-α (pg/mL) | 2.2 ± 1.3 | 2.1 ± 0.5 | 1.8 ± 0.6 | 0.73 |
Values are expressed as mean ± SD. Significant differences between groups are marked with * or # (ANOVA with Tukey's multiple comparison test).
GDM, gestational diabetes mellitus; HDL, high-density lipoproteins; LDL, low-density lipoproteins.