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Sheep groups and immunisation schedule (n = 5). IM – intramuscular administration of 100 μg CN54gp140 + 200 μg R848; IVag – intravaginal administration of 500 μg CN54gp140 ± 500 μg R848.
| Group | Day of Immunisation |
|||
|---|---|---|---|---|
| 0 | 28 | 56 | 84 | |
| 1 | IM | IVag/gp140 + R848 | IVag/gp140 + R848 | IVag/gp140 + R848 |
| 2 | None | IVag/gp140 + R848 | IVag/gp140 + R848 | IVag/gp140 + R848 |
| 3 | IM | IVag/gp140 only | IVag/gp140 only | IVag/gp140 only |
| 4 | None | IVag/gp140 only | IVag/gp140 only | IVag/gp140 only |
| 5 | IM | IM | IM | IM |
