Table 4. Pre-generated paired CRISPR libraries.
| Feature Class | Species | Source | % full depth | % partial depth | Mean pairs per target | Mean sgRNA score | Mean pair score | Mean pair distance | Total sgRNA pairs | # Input targets | # Designed targets |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Random intergenic | Human | Gencode hg37, UCSC, RefSeq | 0.39 | 0.26 | 7 | 0.46 | 0.92 | 1864 | 15952 | 3170 | 2071 |
| Protein coding gene promoters | Human | Gencode hg37 | 0.82 | 0.8 | 9 | 0.6 | 1.22 | 632 | 175116 | 20332 | 18304 |
| Vista enhancers | Human | Vista enhancers browser hg37 | 0.66 | 0.22 | 8 | 0.50 | 1.00 | 2409 | 13236 | 1747 | 1522 |
| Ultraconserved elements | Human | UCNE base hg37 | 0.70 | 0.23 | 8 | 0.49 | 0.99 | 985 | 35240 | 4351 | 4031 |
| Flagged SNPs | Human | GWAS base hg37 | 0.48 | 0.24 | 8 | 0.48 | 0.96 | 1665 | 110135 | 18670 | 13526 |
| CTCF | Human | Gencode hg37 | 0.68 | 0.18 | 8 | 0.53 | 1.06 | 795 | 335315 | 44056 | 37709 |
| MicroRNA | Human | Mirbase hg38 > liftover to hg37 | 0.65 | 0.17 | 8 | 0.53 | 1.06 | 731 | 13788 | 1871 | 1540 |
| MicroRNA | C.elegans | Mirbase ce11 | 0.76 | 0.15 | 9 | 0.55 | 1.09 | 713 | 2093 | 250 | 227 |
| MicroRNA | Zebrafish | Mirbase z9 | 0.49 | 0.16 | 8 | 0.52 | 1.05 | 692 | 1944 | 337 | 221 |
| MicroRNA | Mouse | Mirbase mm10 | 0.73 | 0.10 | 9 | 0.57 | 1.13 | 730 | 9268 | 1187 | 983 |
| MicroRNA | D.melanogaster | Mirbase dm5 | 0.96 | 0.02 | 9 | 0.62 | 1.23 | 760 | 2508 | 256 | 251 |