Table 4. Myocardial injury and function measured by CMR according to osteoprotegerin (OPG) values measured at Day 1.
| OPG < median | OPG > median | P-value | |
|---|---|---|---|
| CMRa in acute phase | n = 113 | n = 112 | |
| Time to CMR (days) | 2 (1, 3) | 2 (1, 3) | 0.67 |
| Infarct size (% of LVb mass) | 15.5 (9.7, 24.6) | 19.7 (12.7, 33.2) | 0.004 |
| Ejection fraction (%) | 52.0 (48.0, 59.0) | 47.5 (38.5, 56.0) | <0.001 |
| Area at risk (% of LV) | 37.6 (31.5, 47.7) | 47.1 (38.6, 55.4) | <0.001 |
| Presence of MVOc | 50 (43.9%) | 60 (57.1%) | 0.05 |
| CMR after 4 months | n = 117 | n = 116 | |
| Time to CMR (months) | 4 (4, 4) | 4 (4, 4) | 0.72 |
| Infarct size (% of LV mass) | 12.3 (6.4, 21.4) | 16.1 (9.3, 24.7) | 0.01 |
| Ejection fraction (%) | 58.0 (50.0, 63.5) | 53.5 (44.5, 60.0) | 0.007 |
| Myocardial Salvage (%) | 54.0 (40.0, 68.3) | 50.4 (34.1, 67.8) | 0.54 |
| Delta EDVd (ml) | 9.0 (-8.3, 24.8) | 9.0 (-7.0, 27.0) | 0.61 |
Data are presented as median (25th, 75th percentiles) or numbers (%). Mann-Whitney U test for continuous variables, Chi-square test for categorical variables. Significant p-values are highlighted in bold. OPG was measured median 14.7 hours after the PCI-procedure.
aCMR: cardiac magnetic resonance imaging
bLV: left ventricle
cMVO: microvascular obstruction
dEDV: end-diastolic volume of LV.