Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Mar 2;12(3):e0173335. doi: 10.1371/journal.pone.0173335

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Wang et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

Fig 6 — A-B: The cell viability of BPH-1 (A) and P69 (B) was markedly enhanced with conditioned medium of 3T3 fibroblast cells, and was abrogated by 5 mM metformin. C: Metformin (5 mM, 24 h) inhibited the secretion of IGF-1 in 3T3 cells. D: Immunoblots of IGF-1R and pho-IGF-1R in BPH-1 cells treated with CM of human prostatic fibroblast. E: The BPH-1 cell viability after treatment with CM of human prostatic fibroblast. F: Metformin (5 mM, 24 h) inhibited the secretion of IGF-1 in human prostatic fibroblasts. *, P<0.05 compared with the control (CTR) group; #, P<0.05 compared with CM-treated group. CTR: non-treated control, Met: metformin.