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. 2017 Mar 9;2(5):e89530. doi: 10.1172/jci.insight.89530

Figure 3. Treg suppressive deficiency correlates with disease burden and rate of disease progression.

Figure 3

(A) There is a correlation between burden of disease (Appel ALS [AALS] points) at blood draw and the level of Treg suppression of responder T lymphocyte (Tresp) proliferation at the 1:1/2 Tresp/Treg ratio. (B) There is a correlation between the rates of disease progression (AALS points/month) at blood draw and Treg suppression of Tresp proliferation. P values obtained by Pearson correlation.

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