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. 2017 Mar 9;2(5):e90063. doi: 10.1172/jci.insight.90063

Figure 5. Eomeshi cells are less mature than T-bethi cells based on granzyme B and perforin expression.

Figure 5

(A) Representative flow cytometry histogram showing median fluorescence intensity (MFI) of granzyme B and perforin expression on 15-week gestational age lung specimen stage 5a cells gated on Eomeshi (blue line) and T-bethi (red line) cells compared to Eomeslo T-betlo (L) stage 3 cells (shaded gray histogram). (B) Mean frequencies ± SEM of granzyme B or perforin MFI on Eomeshi (open circles) and T-bethi (closed circles) cells from indicated tissues and stages. Fetal bone marrow (BM), n = 5; fetal liver, n = 6; fetal lung, n = 7; fetal spleen, n = 6; umbilical cord blood (UCB), n = 6; adult spleen (Adult S.), 4 independent measurements made on n = 2 specimens. Significance determined using 2-way ANOVA with Bonferroni post-hoc tests. *P < 0.05, ***P < 0.001, ****P < 0.0001. ns, not significant.