Table 3. Univariate and Multivariate Analyses of Various Covariates on Local Progression-Free Survival.
| Factor | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
| Median ± SE | p-value | HR | 95% CI | p-value | |
| Gender | 0.956 | ||||
| Male | 20 ± 8.2 | ||||
| Female | 43 ± 17.1 | ||||
| Age (yr) | 0.613 | ||||
| ≤ 55 | 26 ± 15.3 | ||||
| > 55 | |||||
| Primary cancer | 0.031* | 0.111 | |||
| Favourable | 1 | ||||
| Unfavourable | 12 ± 5.3 | 1.929 | 0.86–4.327 | ||
| No. of bone metastases | 0.51 | ||||
| Single | 43 ± 15.7 | ||||
| Multiple | 19 ± 8.7 | ||||
| Visceral metastases | 0.009* | 0.027* | |||
| Absent | 1 | ||||
| Present | 12 ± 5.5 | 2.297 | 1.101–4.795 | ||
| Solitary bone metastasis | 0.18 | ||||
| Yes | |||||
| No | 19 ± 9 | ||||
| Location in the innominate bone | 0.12 | ||||
| Iliac wing | 29 ± 16 | ||||
| Periacetabular | 20 ± 16.2 | ||||
| Ischium | |||||
| Pubic bone | 12 ± 5.3 | ||||
| Entire pelvis | 2 | ||||
| Size (cm) | 0.252 | ||||
| ≤ 6.8 | 47 ± 23.3 | ||||
| > 6.8 | 12 ± 9.6 | ||||
| Soft tissue component | 0.343 | ||||
| Absent | 47 | ||||
| Present | 19 ± 9 | ||||
| Skip lesions | 0.006* | 0.017* | |||
| Absent | 43 ± 15.3 | 1 | |||
| Present | 6 ± 2.7 | 2.556 | 1.184–5.518 | ||
| Pathological fracture | 0.903 | ||||
| Absent | 26 ± 10.5 | ||||
| Present | 43 ± 22.5 | ||||
| Preoperative radiation | 0.569 | ||||
| Received | 19 ± 8.3 | ||||
| Not received | 29 ± 14 | ||||
| Preoperative embolisation | 0.627 | ||||
| Done | 26 ± 10.9 | ||||
| Not done | 43 ± 22.1 | ||||
| Surgical margin | 0.41 | ||||
| En bloc | |||||
| Curettage | 8 ± 1.3 | ||||
| Histological margin | 0.748 | ||||
| Negative | 12 ± 4.1 | ||||
| Positive | 29 ± 12.7 | ||||
| Postoperative radiation | 0.131 | ||||
| Received | 47 ± 12.8 | ||||
| Not received | 12 ± 3.6 | ||||
SE: standard error, HR: hazards ratio, CI: confidence interval.
*Statistically significant.