Table 1. Clinical characteristics of patients with adenocarcinoma (ACA), adenosquamous carcinoma (ASC) and squamous cell carcinoma (SqCC).
| Characteristic | ACA (%) | SqCC (%) | ASC (%) | Total (%) | P value |
|---|---|---|---|---|---|
| Count | 18,110 (60.6) | 11,496 (38.5) | 284 (1.0) | 29,890 (100.0) | |
| Age (years)/SEM | 66.4/13.8 | 67.3/11.5 | 65.3/11.3 | 66.8/13.0 | |
| Gender | <0.001 | ||||
| Male | 15,610 (86.2) | 7,531 (65.5) | 239 (84.2) | 23,380 (78.2) | |
| Female | 2,500 (13.8) | 3,965 (34.5) | 45 (15.8) | 6,510 (21.8) | |
| Race | <0.001 | ||||
| White | 17,246 (95.2) | 7,370 (64.1) | 244 (85.9) | 24,860 (83.2) | |
| Black | 445 (2.5) | 3,015 (26.2) | 24 (8.5) | 3,484 (11.7) | |
| Other | 419 (2.3) | 1,111 (9.7) | 16 (5.6) | 1,546 (5.2) | |
| Grade | <0.001 | ||||
| I/II | 7,112 (39.3) | 4,850 (42.2) | 44 (15.5) | 12,006 (40.2) | |
| III/IV | 8,107 (44.8) | 4,591 (39.9) | 207 (72.9) | 12,905 (43.2) | |
| Unknown | 2,891 (16.0) | 2,055 (17.9) | 33 (11.6) | 4,979 (16.7) | |
| SEER historic stage | <0.001 | ||||
| Localized | 4,980 (27.5) | 3,212 (27.9) | 41 (14.4) | 8,233 (27.5) | |
| Regional | 5,823 (32.2) | 4,323 (37.6) | 106 (37.3) | 10,252 (34.3) | |
| Distant | 7,307 (40.3) | 3,961 (34.5) | 137 (48.2) | 11,405 (38.2) | |
| AJCC staging (2004+) | <0.001 | ||||
| I/IIa | 3,665 (32.4) | 2,152 (34.6) | 32 (20.1) | 5,849 (33.1) | |
| IIb–IVa | 3,966 (35.1) | 2,528 (40.7) | 65 (40.9) | 6,559 (37.1) | |
| IVb | 3,669 (32.5) | 1,535 (24.7) | 62 (39.0) | 5,266 (29.8) | |
| Primary site | <0.001 | ||||
| Cervical/upper | 253 (1.4) | 1,999 (17.4) | 12 (4.2) | 2,264 (7.6) | |
| Thoracic/middle | 1,459 (8.1) | 4,590 (39.9) | 60 (21.1) | 6,109 (20.4) | |
| Abdominal/lower | 14,451 (79.8) | 3,292 (28.6) | 177 (62.3) | 17,920 (60.0) | |
| Esophagus, NOS | 1,947 (10.8) | 1,615 (14.0) | 35 (12.3) | 3,597 (12.0) | |
| Surgery | <0.001 | ||||
| Resection | 5,637 (31.1) | 1,826 (15.9) | 93 (32.7) | 7,556 (25.3) | |
| No resection | 12,473 (68.9) | 9,670 (84.1) | 191 (67.3) | 22,334 (74.7) | |
| LN examined | <0.001 | ||||
| No | 12,123 (66.9) | 9,237 (80.3) | 191 (67.3) | 21,551 (72.1) | |
| Yes | 5,801 (32.0) | 2,157 (18.8) | 92 (32.4) | 8,050 (26.9) | |
| Radiation | <0.001 | ||||
| No | 8,502 (46.9) | 4,125 (35.9) | 128 (45.1) | 12,755 (42.7) | |
| Yes | 9,608 (53.1) | 7,371 (64.1) | 156 (54.9) | 17,135 (57.3) |
SEM, standard error of mean; NOS, not otherwise specified; LN, lymph nodes.