Table 2. Variables associated with overall survival in univariate and multivariate analysis for all patients.
| Variable | Reference level | HR (95% CI) | |
|---|---|---|---|
| Univariate analysis | Multivariate analysis | ||
| Age | 1.01 (1.00–1.01) | 1.01 (1.01–1.01) | |
| Grade | |||
| III/IV | I/II | 1.32 (1.29–1.36) | 1.22 (1.19–1.26) |
| Unknown | I/II | 1.08 (1.04–1.13) | 0.93 (0.90–0.97) |
| Stage | |||
| Distant | Localized | 2.90 (2.80–3.00) | 2.44 (2.35–2.52) |
| Regional | Localized | 1.36 (1.31–1.41) | 1.63 (1.57–1.69) |
| Nodes examined | |||
| Unknown | No | 1.07 (0.95–1.21) | 0.96 (0.85–1.09) |
| Yes | No | 0.41 (0.40–0.43) | 0.78 (0.74–0.82) |
| Race | |||
| Black | White | 1.31 (1.26–1.36) | 1.15 (1.10–1.20) |
| Other | White | 1.08 (1.02–1.15) | 0.95 (0.90–1.01) |
| Radiation | |||
| Yes | No | 0.76 (0.74–0.78) | 0.62 (0.60–0.63) |
| Gender | |||
| Female | Male | 1.02 (0.99–1.05) | 0.95 (0.92–0.98) |
| Histology | |||
| ACA | ASC | 0.76 (0.67–0.87) | 0.86 (0.76–0.98) |
| SqCC | ASC | 0.93 (0.81–1.06) | 0.96 (0.84–1.09) |
| Site | |||
| Lower/abdominal | Upper/cervical | 0.91 (0.86–0.95) | 1.06 (1.01–1.12) |
| NOS | Upper/cervical | 1.24 (1.17–1.32) | 1.20 (1.13–1.27) |
| Mid/thoracic | Upper/cervical | 1.07 (1.01–1.13) | 1.10 (1.04–1.16) |
| Surgery | |||
| No resection | Resection | 2.84 (2.74–2.93) | 2.06 (1.94–2.18) |
ACA, adenocarcinoma; ASC, adenosquamous carcinoma; SqCC, squamous cell carcinoma; HR, hazard ratio; CI, confidence interval; NOS, not otherwise specified.