Table 2. Results of binary logistic regression on factors affecting leakage healing.
| Parameter | Fast healing | Slowly healing | P value |
|---|---|---|---|
| Male/female | 33/4 | 46/8 | 0.488 |
| Age (years) | 47–81 (62.8) | 46–83 (62.1) | 0.624 |
| Preoperative chemotherapy | 4 | 2 | 0.308 |
| Smoking index (≤400) | 23 | 39 | 0.040 (OR =1.001) |
| Drinking | 18 | 28 | 0.177 |
| Hypoproteinemia preoperative | 10 | 5 | 0.582 |
| Low preoperative lung function | 10 | 21 | 0.134 |
| HPN/CAD | 5 | 18 | 0.551 |
| Diabetes | 3 | 9 | 0.161 |
| Duration of fever (days) | 1–18 (5.1) | 1–21 (6.5) | 0.084 |
| Duration of antibiotics (days) | 6–22 (11.5) | 6–20 (11.7) | 0.353 |
| Thoracic drainage | 35 | 45 | 0.037 (OR =12.937) |
| Enteral nutrition | 35 | 54 | 0.999 |
| Hypoproteinemia after leak | 34 | 10 | 0.169 |
| Leakage size (<2 cm) | 37 | 44 | 0.004 (OR=1.073) |
Hypoproteinemia: albumin (ALB) <35 mmol/L; smoking index: smoking volume × smoking history (years). HPN, hypertension; CAD, coronary atherosclerosis diseases.