Table 3. Comparison of clinical, laboratory, and imaging characteristics in patients with SRAD and patients with an embolism.
| Characteristics | SRAD (n = 6) | Embolism (n = 14) | P |
|---|---|---|---|
| Age, yr | 56.5 (39–78) | 62.8 (32–85) | 0.387† |
| Male sex | 5 (80.0) | 10 (71.4) | 1.000* |
| Past history | |||
| Diabetes mellitus | 1 (16.7) | 5 (35.7) | 0.613* |
| Hypertension | 1 (16.7) | 4 (28.6) | 1.000* |
| Cardiomyopathy | 0 (0) | 3 (21.4) | 0.521* |
| Heart valve disease | 2 (33.3) | 3 (21.4) | 0.613* |
| Coronary artery disease | 0 (0) | 3 (21.4) | 0.521* |
| Malignancy | 0 (0) | 4 (28.6) | 0.267* |
| Blood pressure, mmHg | |||
| Systolic | 157.3 ± 18.0 | 149.5 ± 33.2 | 0.092† |
| Diastolic | 80.0 ± 16.9 | 76.3 ± 12.9 | 0.379† |
| Mean | 105.8 ± 12.8 | 94.6 ± 19.0 | 0.184† |
| New-onset hypertension | 5 (83.3) | 3 (21.4) | 0.018* |
| Bilateral renal involvement | 0 (0) | 9 (64.3) | 0.014* |
| Laboratory finding | |||
| Creatinine, mg/dL | 0.95 ± 0.08 | 1.28 ± 0.77 | 0.214† |
| BUN, mg/dL | 13.9 ± 2.8 | 28.2 ± 21.6 | 0.009† |
| BUN/creatinine | 14.8 ± 3.2 | 22.5 ± 8.9 | 0.025† |
| eGFR, mL/min/1.73 m2 | 85.9 ± 8.1 | 68.4 ± 26.1 | 0.105† |
| LDH, U/L | 210.2 ± 64.6 | 415.3 ± 269.7 | 0.012† |
| WBC (> 104/mm3) | 0 (0) | 6 (42.9) | 0.115* |
| CRP (> 0.3 mg/dL) | 0 (0) | 11 (78.6) | 0.002* |
| Coagulation study | |||
| PT (> 13.2 sec) | 0 (0) | 5 (35.7) | 0.260* |
| PT (> 1.2 INR) | 0 (0) | 5 (35.7) | 0.260* |
| aPTT (> 37 sec) | 2 (33.3) | 3 (21.4) | 0.613* |
| Urinalysis | |||
| Proteinuria | 3 (50.0) | 7 (50.0) | 1.000* |
| Pyuria | 2 (33.3) | 10 (71.4) | 0.161* |
| Hematuria | 3 (50.0) | 9 (64.3) | 0.642* |
Values for categorical variables are given as a number (percentage); values for continuous variables, as mean ± standard deviation or median (range); P < 0.05 indicates statistical significance.
SRAD = spontaneous renal artery dissection, BUN = blood urea nitrogen, eGFR = estimated glomerular filtration rate, LDH = lactate dehydrogenase, WBC = white blood cell, CRP = C-reactive protein, PT = prothrombin time, INR = international normalized ratio, aPTT = activated partial thromboplastin time.
*Fisher's exact test; †Mann-Whitney test.