Fig. 3.

A_2A is required for in vitro angiogenesis. HUVECs were isolated from normal pregnancies and used for in vitro angiogenesis assays. a Representative images of in vitro angiogenesis in the presence (+) of CGS-21680 (10⁻⁸ M) and/or SNAP (10⁻⁹ M) in control conditions or in cells exposed to siRNA for adenosine receptor (siRNA-A_2A). b Quantification of the length of the tubes in basal conditions (open bar) and in the presence of siRNA-A_2A (hatched bar). Results are expressed as medians and interquartile ranges. In b, *p < 0.05 vs baseline. †p < 0.05 vs respective values in non-transfected cells, n = 3 for each assay in duplicate