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Figure 2.

Figure 2.

Chemical structures of compounds recently used in clinical trials and recently developed representative lead compounds. Compounds used in clinical trials include (A) flupirtine, (B) quinacrine, (C) pentosan polysulfate (PPS), and (D) doxycycline. Representative lead compounds include (E) compB, (F) IND24, (G) IND81, and (H) anle138b.