Table 3.
Multivariate Cox regression analysis showing the predictors of new‐onset diabetes after transplantation in liver transplant recipients
| Variables | HR | 95% CI | P‐value |
|---|---|---|---|
| NODAT | |||
| Preoperative FPG | 1.765 | 1.209–2.577 | 0.003* |
| FK506 (3–12 months after LT) | 1.110 | 1.013–1.216 | 0.026* |
| Donor liver steatosis | 1.774 | 1.025–3.073 | 0.041* |
| Early NODAT | |||
| Preoperative FPG levels | 2.152 | 1.411–3.283 | <0.001* |
| Donor liver steatosis | 1.987 | 1.045–3.780 | 0.036* |
| Late NODAT | |||
| FK506 (3–12 months after LT) | 1.422 | 1.060–1.907 | 0.019* |
Variables were analyzed after adjusting for age; sex; donor type; hepatitis virus infection; body mass index; history of hypertension; preoperative liver function; preoperative levels of fasting plasma glucose, total cholesterol and total triglycerides; severity of liver cirrhosis; acute rejection; postoperative transaminase levels; initial immunosuppressant type; and postoperative immunosuppressant levels. *P < 0.05. CI, confidence interval; FK506, tacrolimus; FPG, fasting plasma glucose; HR, hazard ratio; LT, liver transplantation; NODAT, new‐onset diabetes after transplantation.