Table 4.
Multiple linear regression analyses determining plasma stromal cell‐derived factor‐1α changes
| Independent variables | β | P‐value |
|---|---|---|
| Model 1† | ||
| Vildagliptin | −0.532 | <0.001 |
| ΔLDL‐C | 0.218 | 0.125 |
| ΔLog(IL‐6) | 0.327 | 0.018 |
| ΔLog(CONGA‐6) | 0.214 | 0.141 |
| Model 2‡ | ||
| Vildagliptin | −0.528 | <0.001 |
| ΔLDL‐C | 0.211 | 0.146 |
| ΔLog(IL‐6) | 0.319 | 0.024 |
| ΔLog(CONGA‐6) | 0.239 | 0.125 |
| 1,5‐AG | −0.073 | 0.604 |
| Model 3§ | ||
| Vildagliptin | −0.572 | <0.001 |
| ΔLDL‐C | 0.317 | 0.027 |
| ΔLog(IL‐6) | 0.352 | 0.027 |
| ΔLog(BNP) | −0.114 | 0.465 |
| Model 4¶ | ||
| Vildagliptin | −0.534 | 0.001 |
| ΔLDL‐C | 0.221 | 0.135 |
| ΔLog(IL‐6) | 0.345 | 0.027 |
| ΔLog(CONGA‐6) | 0.195 | 0.224 |
| Age | 0.010 | 0.947 |
| Sex | −0.049 | 0.752 |
†Adjusted R 2 = 0.489, F = 8.418; P < 0.001. ‡Adjusted R 2 = 0.475, F = 6.609; P < 0.001. §Adjusted R 2 = 0.457, F = 7.510; P < 0.001. ¶Adjusted R 2 = 0.451, F = 5.241; P = 0.001. 1,5‐AG, 1,5‐anhydroglucitol; BNP, B‐type natriuretic peptide; CONGA‐6, continuous overlapping net glycemic action calculated with 6‐h time intervals; IL‐6, interleukin‐6; LDL‐C, low‐density lipoprotein cholesterol.