Table 1.
Brain areas of significant BOLD response across Group 1 subjects.
| Networks | Ipsilateral | Size (mm3) | Z-score | Contralateral | Size (mm3) | Z-score |
|---|---|---|---|---|---|---|
| Associative | Anterior prefrontal cortex (I) | 1,050 | 13.83 | Anterior prefrontal cortex (I) | 31 | −8.91 |
| Dorsolateral prefrontal cortex (I) | 771 | 14.93 | Dorsolateral prefrontal cortex (I) | 44 | −9.26 | |
| Limbic | Prepyriform area (I) | 54 | −7.47 | Prepyriform area (I) | 64 | −10.85 |
| Insular cortex | 119 | 14.26 | Insular cortex | 49 | −9.11 | |
| Dorsal anterior cingulate cortex (I) | 442 | 13.86 | ||||
| Dorsal posterior cingulate cortex (I) | 167 | 15.60 | ||||
| Nucleus Accumbens (I) | 94 | 7.97 | ||||
| Perirhinal cortex (I) | 3 | −6.73 | ||||
| Fornix and hippocampus (C) | 33 | 7.69 | ||||
| Inferior temporal gyrus (C) | 72 | −9.11 | ||||
| Parahippocampal cortex (C) | 44 | −9.72 | ||||
| Sensory/motor | Primary somatosensory cortex (I) | 900 | 14.24 | Primary somatosensory cortex (I) | 142 | −8.72 |
| Premotor cortex (I) | 1,041 | 16.96 | ||||
| Primary motor cortex (I) | 230 | 15.62 | ||||
| Cerebellar lobule V (C) | 42 | 7.58 | ||||
| Cerebellar lobule VI (C) | 59 | 7.62 | ||||
| Cerebellar lobule VIIB (C) | 29 | 7.6 | ||||
| Basal ganglia | Caudate (I) | 2 | 6.31 | |||
| Putamen (I) | 169 | 11.47 |
Associative network activation included the anterior prefrontal cortex on both the ipsilateral and contralateral side. Limbic regions of significant BOLD change included dorsolateral prefrontal cortex, prepyriform area, insular cortex (bilateral), dorsal anterior cingulate cortex, dorsal posterior cingulate cortex, nucleus accumbens, perirhinal cortex (ipsilateral), fornix and hippocampus, inferior temporal gyrus, parahippocampal cortex (contralateral). Sensory/motor regions included primary somatosensory cortex (bilateral), premotor and primary motor cortex (ipsilateral), and cerebellar lobules V, VI, VIIB (contralateral). Basal ganglia regions included ipsilateral caudate and putamen.