Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Cytotoxicity of cisplatin and analogs is p53-dependent. IC50 values of cisplatin, DAP and oxaliplatin were determined in sensitive A2780 and resistant 2780CP/Cl-16 and 2780CP/Cl-24 cells (A) or HCT-116 p53−/− and HCT-116 p53+/+ cells (B) using the MTT assay. The results are shown as mean ± SD of three independent experiments.
