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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Am J Obstet Gynecol. 2016 Nov 12;216(3):304.e1–304.e16. doi: 10.1016/j.ajog.2016.11.1009

Table 1.

Odds ratios and 95% confidence intervals for the association of ASD+/ID−, ASD+/ID+, ASD−/ID+ and ASD−/ID− with the antecedents listed on the left calculated using a time-oriented multinomial logistic regression model that added variables sequentially as they were identified. Earlier occurring variables that were significantly associated could not be displaced in later models.

ASD+/ID−
ASD+/ID+
ASD−/ID+
ASD−/ID−
(n = 27) (n = 32) (n = 71) (n = 710)
Pregnancy epoch*
Cervical-vaginal infection 0.9 (0.2, 4.1) 2.7 (1.2, 6.4) 0.7 (0.3, 1.6) 1.0
Receipt of antibiotic 0.1 (0.01, 0.7) 0.8 (0.4, 1.9) 1.3 (0.9, 2.3) 1.0
Delivery epoch**
Fever at delivery 3.6 (0.98, 13) 0.6 (0.1, 4.4) 2.9 (1.2, 6.7) 1.0
Newborn epoch***
Male 2.1 (0.9, 5.0) 2.9 (1.3, 6.8) 2.1 (1.2, 3.6) 1.0
GA 23-24 weeks 4.4 (1.7, 11) 2.9 (1.3, 6.6) 1.8 (1.03, 3.3) 1.0
BW Z-score < −2 9.9 (3.3, 30) 2.1 (0.5, 9.9) 2.0 (0.7, 5.3) 1.0
*

Both fixed effects (independent variables) were included in the same multinomial logistic regression model

**

Adjusted for fixed effects that were significantly associated with ASD−/ID+ risk in the pregnancy epoch model

***

Adjusted for fixed effects that were significantly associated with ASD−/ID+ risk in the pregnancy and delivery epoch models

odds ratios above 1.0 are interpreted as indicating increased risk of the outcome listed at the top of the column for women or children who were exposed to what is described on the left, whereas odds ratios below 1.0 indicate decreased risk, and confidence intervals that do not include 1.0 indicate statistically significant associations (indicated by bold font).