Table 2.
Cohen’s d effect size measurements for age differences in OTR and V1aR binding densities overall, and analyzed separately in males and females
| OTR/V1aR | Direction | Both sexes | Males | Females | |
|---|---|---|---|---|---|
| Cortical areas | |||||
| aAIP | OTR | Higher in adults | −1.92 | −2.64 | −1.89 |
| mAIP | OTR | Higher in adults | −1.29 | −1.66 | −1.09 |
| Il | OTR | Higher in adults | −0.79 | −0.72 | −0.82 |
| Pir | V1aR | Higher in adults | −1.03 | −0.93 | −1.15 |
| PRh | OTR | Higher in adults | −1.08 | −1.49 | −0.78 |
| PRL | OTR | Higher in adults | −1.21 | −1.05 | −1.56 |
| S1 | V1aR | Higher in adults | −1.35 | −1.38 | −1.40 |
| Olfactory areas | |||||
| AOM | OTR | Higher in juveniles | 1.56 | 1.90 | 1.26 |
| AOPV | OTR | Higher in juveniles | 2.01 | 2.07 | 2.30 |
| AODL | V1aR | Higher in juveniles | 1.19 | 1.00 | 1.37 |
| NV | V1aR | Higher in adults | −1.03 | −1.32 | −0.65 |
| Striatal areas | |||||
| aAcbC | OTR | Higher in juveniles | 2.62 | 2.29 | 2.92 |
| pAcbSh | V1aR | Higher in adults | −2.00 | −1.52 | −2.79 |
| dCPu | OTR | Higher in juveniles | 2.84 | 2.71 | 3.10 |
| mCPu | OTR | Higher in juveniles | 0.73 | 0.69 | 0.73 |
| pCPu | OTR | Higher in adult females | −0.51 | 0.20 | −1.17 |
| Icj | OTR | Higher in adult males | −1.73 | −6.79 | −0.90 |
| Icj | V1aR | Higher in juveniles | 1.01 | 1.35 | 0.71 |
| VP | V1aR | Higher in adults | −1.50 | −1.50 | −1.49 |
| Lateral septum | |||||
| LSD | V1aR | Higher in adults | −1.25 | −1.46 | −1.54 |
| LSV | OTR | Higher in juveniles | 1.70 | 2.62 | 1.20 |
| BNST | |||||
| BNSTp | OTR | Higher in adults | −0.44 | −1.28 | −0.21 |
| Amygdala | |||||
| BLA | OTR | Higher in juveniles | 0.76 | 1.19 | 0.38 |
| BMA | OTR | Higher in juveniles | 0.82 | 1.34 | 0.23 |
| CeA | V1aR | Higher in juveniles | 0.95 | 1.07 | 0.91 |
| Cl | V1aR | Higher in juveniles | 1.52 | 1.54 | 1.48 |
| IPAC | V1aR | Higher in adults | −0.78 | −0.69 | −0.83 |
| MePD | OTR | Higher in adults | −0.52 | −2.81 | 0.10 |
| Hypothalamus | |||||
| Arc | V1aR | Higher in adults | −1.56 | −2.31 | −1.8 |
| MMN | OTR | Higher in juveniles | 1.76 | 2.95 | 1.17 |
| MPOA | OTR | Higher in adults | −1.99 | −2.16 | −2.04 |
| PVN | OTR | Higher in juveniles | 1.13 | 1.13 | 1.44 |
| SMN | OTR | Higher in juveniles | 1.27 | 1.78 | 0.76 |
| Stg | V1aR | Higher in adults | −1.13 | −1.17 | −1.04 |
| VMH | OTR | Higher in adults | −3.75 | −5.25 | −3.99 |
| Thalamus | |||||
| PVT | OTR | Higher in juveniles | 1.93 | 1.82 | 2.07 |
| SPFPC | OTR | Higher in juveniles | 1.20 | 1.38 | 0.92 |
| vmThal | V1aR | Higher in adults | −2.51 | −3.99 | −2.73 |
| Hippocampus | |||||
| DS | OTR | Higher in juveniles | 2.70 | 2.87 | 2.49 |
| VS | OTR | Higher in juveniles | 1.72 | 1.25 | 2.31 |
| dDG | V1aR | Higher in juveniles | 2.66 | 2.41 | 2.88 |
| vDG | V1aR | Higher in juveniles | 1.30 | 1.44 | 1.14 |
| Midbrain | |||||
| MA3 | V1aR | Higher in juveniles | 0.94 | 1.14 | 0.66 |
Only brain regions showing significant main effects of age or interaction (see Table 1) are included