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. 2016 Jun 14;27(4):1556–1567. doi: 10.1007/s00330-016-4451-y

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 4 — Representative case of a LGG with positive IDH1-R132H mutational status. (A) Preoperative axial T2-weighted MR images and (B) contrast-enhanced T1-weighted sequences demonstrate a left frontal hyperintense lesion with non-significant (patchy/faint) CE. (C) 7 Tesla SWI detects only very few hypointense structures and (D) the corresponding colour-coded SWI-LIV map shows low values in the tumour ROI (mean SWI-LIV: 32.2). (E) Histopathological examination reveals a LGG (diffuse astrocytoma WHO grade II) with (F) positive IDH1-R132H mutational status. Original magnification of the H&E stain (E) and IDH1-R132H stain (F) is × 200