Fig. 2.

Distinct localization of SK2 proteins in human brain detected with Anti-NSK2. In hippocampus, SK2-LI was most prominent in the stratum oriens and pyramidale of the CA1–CA2 region and in stratum moleculare (a). In the amygdala, SK2 protein was mainly detected in the basolateral nuclei (b). In neocortex, SK2-LI was mainly detected in pyramidal cells of layer V (c). The immunostaining signal was blocked by pre-incubation with the corresponding peptide (inlay in a). sr stratum radiatum, sp stratum pyramidale, so stratum oriens, slm stratum lacunosum moleculare, sm stratum moleculare, gl granule cell layer, BLA basolateral amygdala, I–VI layers of the neocortex. Scale bars 500 µm in a, b; 250 µm in c